Predicting the likelihood of successful medical treatment of early pregnancy loss: development and internal validation of a clinical prediction model.

ABSTRACT:

Study question

What are clinical predictors for successful medical treatment in case of early pregnancy loss (EPL)?

Summary answer

Use of mifepristone, BMI, number of previous uterine aspirations and the presence of minor clinical symptoms (slight vaginal bleeding or some abdominal cramps) at treatment start are predictors for successful medical treatment in case of EPL.

What is known already

Success rates of medical treatment for EPL vary strongly, between but also within different treatment regimens. Up until now, although some predictors have been identified, no clinical prediction model has been developed yet.

Study design, size, duration

Secondary analysis of a multicentre randomized controlled trial in 17 Dutch hospitals, executed between 28 June 2018 and

SUBMITTER: Hamel CC 

PROVIDER: S-EPMC9071219 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature