Consensus core clinical data elements for meningiomas (v2021.1).

ABSTRACT:

Background

With increasing molecular analyses of meningiomas, there is a need to harmonize language used to capture clinical data across centers to ensure that molecular alterations are appropriately linked to clinical variables of interest. Here the International Consortium on Meningiomas presents a set of core and supplemental meningioma-specific common data elements (CDEs) to facilitate comparative and pooled analyses.

Methods

The generation of CDEs followed the 4-phase process similar to other National Institute of Neurological Disorders and Stroke (NINDS) CDE projects: discovery, internal validation, external validation, and distribution.

Results

The CDEs were organized into patient- and tumor-level modules. In total, 17 core CDEs (10 patient level and 7 tumor le

SUBMITTER: Nassiri F 

PROVIDER: S-EPMC9071284 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature