Utility of interval kidney biopsy in ANCA-associated vasculitis.

ABSTRACT:

Objectives

ANCA-associated vasculitis (AAV) is a rare autoimmune disorder that commonly involves the kidney. Early identification of kidney involvement, assessing treatment-response and predicting outcome are important clinical challenges. Here, we assessed the potential utility of interval kidney biopsy in AAV.

Methods

In a tertiary referral centre with a dedicated vasculitis service, we identified patients with AAV who had undergone interval kidney biopsy, defined as a repeat kidney biopsy (following an initial biopsy showing active AAV) undertaken to determine the histological response in the kidney following induction immunosuppression. We analysed biochemical, histological and outcome data, including times to kidney failure and death for all patients.

Results

We

SUBMITTER: Chapman GB 

PROVIDER: S-EPMC9071515 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature