Pretreatment tumor sampling and prognostic factors in patients with soft-tissue sarcoma of the head and neck.

ABSTRACT:

Background

Insufficient preoperative work-up and consequent intralesional or marginal resection of soft-tissue sarcomas of the head and neck (STSHNs) is common.

Methods

This retrospective cohort study comprised 63 patients with STSHN treated at the Helsinki University Hospital between 2005 and 2017. We assessed the effect of pretreatment tumor sampling on surgical margin status and need for supplemental surgery, as well as prognostic factors and survival.

Results

The lack of representative pretreatment biopsy specimen was associated with unfavorable margin status. Primary surgery at a non-academic center was associated with need for supplemental surgery. The 3-year overall survival (OS) was 68%, disease-specific survival (DSS) 71%, and recurrence-free survival (RFS) 6

SUBMITTER: Roos JH 

PROVIDER: S-EPMC9072459 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature