Graphene quantum dots mediated electron transfer in DNA base pairs.

ABSTRACT: Graphene quantum dots (GQDs) were connected to [Ru(bpy)₃]²⁺ to sense DNA-mediated charge transfer. Interaction between abasic site double stranded DNA (Abasic-DNA) and [Ru(bpy)₃-GQD]²⁺ was investigated by absorption spectroscopy, gel electrophoresis, circular dichroism, and melting temperature measurements. The results indicate that [Ru(bpy)₃-GQD]²⁺ could be intercalated into double stranded DNA. Using [Ru(bpy)₃-GQD]²⁺ as a signal molecule, the charge transfer performance of DNA-intercalated [Ru(bpy)₃-GQD]²⁺ was determined using electrochemical and electrochemiluminescence measurements. Various DNA types were immobilized on Au electrodes via Au-S bonds. Electrochemiluminesce

SUBMITTER: Liu C 

PROVIDER: S-EPMC9072722 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature