Contralesional Sensorimotor Network Participates in Motor Functional Compensation in Glioma Patients.

ABSTRACT:

Background

Some gliomas in sensorimotor areas induce motor deficits, while some do not. Cortical destruction and reorganization contribute to this phenomenon, but detailed reasons remain unclear. This study investigated the differences of the functional connectivity and topological properties in the contralesional sensorimotor network (cSMN) between patients with motor deficit and those with normal motor function.

Methods

We retrospectively reviewed 65 patients (32 men) between 2017 and 2020. The patients were divided into four groups based on tumor laterality and preoperative motor status (deficit or non-deficit). Thirty-three healthy controls (18 men) were enrolled after matching for sex, age, and educational status. Graph theoretical measurement was applied to reveal alte

SUBMITTER: Fang S 

PROVIDER: S-EPMC9072743 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature