Serum Human Epididymis Protein 4 as a Prognostic Marker in Cervical Cancer.

ABSTRACT:

Objectives

The objective is to evaluate the prognostic value of serum human epididymis protein 4 (HE4) as a tumor marker in patients with cervical cancer.

Methods

Sixty-seven patients with cervical cancer treated at Seoul National University Bundang Hospital from September 2014 to May 2018 were retrospectively reviewed. Serum HE4 levels were measured by immunoassay before starting primary treatment. A mean serum HE4 level of 72.6 pmol/L was used to divide the patients into low and high HE4 groups. Patient characteristics, clinicopathological variables, and survival outcomes were compared between the two groups.

Results

The low and high HE4 groups included 55 (82.1%) and 12 (17.9%) patients at diagnosis, respectively. Higher HE4 levels were significantly associated wit

SUBMITTER: Hwang WY 

PROVIDER: S-EPMC9072869 | biostudies-literature | 2022 Jan-Dec

REPOSITORIES: biostudies-literature