Preksha Dhyana meditation induces alterations at the transcriptome level in novice and healthy college students.

ABSTRACT:

Background

The human transcriptome across a variety of cell types and tissues are affected by stress and other psychological factors. Preksha Dhyana meditation (PM) is effective at improving cognitive skills in novice healthy college student meditators after 8 weeks of intervention, but the molecular and cellular mechanisms involved in these improvements are still largely unknown.

Methods

In order to decipher potential mechanisms at the cellular level, transcriptomic profiling analyses, from peripheral blood, were performed at baseline and 8 weeks post-intervention in 18-paired participants (RNASeq).

Results

At the transcriptomic level, 494 genes were nominally differentially expressed (p-value ≤ 0.05) between baseline and 8 weeks post-intervention. Our

SUBMITTER: Abomoelak B 

PROVIDER: S-EPMC9072888 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature