Cardioprotective properties of Artemisia herba alba nanoparticles against heart attack in rats: A study of the antioxidant and hypolipidemic activities.

ABSTRACT: Recently, pharmaceutical scientists' interest has increased to find novel pharmaceutical natural substances with potent antioxidant capacity and very low side effects to be used safely in preventive medicine. One of the most common types of diseases with a large spread globally is cardiovascular diseases, which cause a high rate of deaths annually. The present study evaluated the use of Artemisia herba alba leaves' extract (AHALE) and AHALE zinc oxide nanoparticles (AHALE-ZnONPs) against isoproterenol (ISO) inducing myocardial infarction (MI) in male rats. Several groups of Wistar male rats fed a high-fat diet (HFD) were pretreated with several doses of AHALE or AHALE-ZnONPs for one month followed by exposure to ISO for two days. After treatment, samples of the rats' h

SUBMITTER: Alshehri MA 

PROVIDER: S-EPMC9072917 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature