Identification of ceftazidime interaction with bacteria in wastewater treatment by Raman spectroscopic mapping.

ABSTRACT: Raman spectroscopy yields a fingerprint spectrum and is of great importance in medical and biological sciences as it is non-destructive, non-invasive, and available in the aqueous environment. In this study, Raman spectroscopy and Raman mapping were used to explore the dynamic biochemical processes in screened bacteria under ceftazidime stress. The Raman spectral difference between bacteria with and without antibiotic stress was analyzed by principal component analysis and characteristic peaks were obtained. The results showed that amino acids changed first and lipids were reduced when bacteria were exposed to ceftazidime stress. Furthermore, in Raman mapping, when bacteria were subjected to antibiotic stress, the peak at 1002 cm^-1 (phenylalanine) increased, while the peak at 11

SUBMITTER: Peng MW 

PROVIDER: S-EPMC9073089 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature