An ionophore-based persistent luminescent 'Glow Sensor' for sodium detection.

ABSTRACT: Optical sensors have numerous positive attributes such as low invasiveness, miniaturizability, biocompatibility, and ease of signal transduction. Recently, there has been a strong research focus on using phosphorescent readout mechanisms, specifically from long-lifetime phosphorescent or 'persistent luminescence' particles, for in vitro and in vivo sensors. Persistent luminescence readouts can avoid cellular autofluorescence during biological monitoring, leading to an improved signal-to-noise ratio over a more traditional fluorescence readout. In this study, we show for the first time an ionophore-based optical bulk optode sensor that utilizes persistent luminescence microparticles for ion detection. To achieve this, we combined long-lifetime strontium aluminate-based 'glow-i

SUBMITTER: Ferris MS 

PROVIDER: S-EPMC9073184 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature