A Systematic Review Comparing Animal and Human Scarring Models.

ABSTRACT:

Introduction

A reproducible, standardised model for cutaneous scar tissue to assess therapeutics is crucial to the progress of the field. A systematic review was performed to critically evaluate scarring models in both animal and human research.

Method

All studies in which cutaneous scars are modelling in animals or humans were included. Models that were focused on the wound healing process or those in humans with scars from an existing injury were excluded. Ovid Medline^® was searched on 25 February 2019 to perform two near identical searches; one aimed at animals and the other aimed at humans. Two reviewers independently screened the titles and abstracts for study selection. Full texts of potentially suitable studies were then obtained for analysis.

Results

SUBMITTER: Mistry R 

PROVIDER: S-EPMC9073696 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature