Osimertinib as induction therapy for oligometastatic non-small cell lung cancer with EGFR mutation: a case report.

ABSTRACT:

Background

The role of surgery in combined modality therapy for selected stage IV oligometastatic (OM) non-small cell lung cancer (NSCLC) is still controversial. Tyrosine kinase inhibitors (TKIs) targeting epidermal growth factor receptor (EGFR) significantly improved the survival in adjuvant therapy in metastatic NSCLC but has rare evidence in inductive setting. This is the first case report about uniportal video-assisted thoracic surgery after induction therapy of TKI for OM-NSCLC.

Case description

A 50-year-old Chinese woman presented to hospital with headache and blurred vision and was diagnosed with an intracranial tumor. The craniotomy confirmed the metastasis from primary lung cancer. Positron emission tomography/computed tomography (PET/CT) showed the mass located in

SUBMITTER: Wu H 

PROVIDER: S-EPMC9073747 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature