Mortality from bladder cancer in dyestuff workers exposed to aromatic amines: A 73-year follow-up.

ABSTRACT:

Objective

To update the analysis of mortality of a cohort of dyestuff workers, in Northern Italy, heavily exposed to carcinogenic aromatic amines.

Methods

We updated to 2018 overall and cause-specific mortality in a cohort of 590 male workers heavily exposed to carcinogenic aromatic amines in a dyestuff factory from 1922 to 1972. Workers were censored at age 85. Expected cases for the period 1946-2018 were computed using Piedmont mortality rates and standardized mortality ratios (SMR) were computed.

Results

Between 1946 and 2018, 470 deaths were reported. The overall SMR was 1.59 (95% confidence interval [CI] 1.45-1.74) and SMR from all cancers was 2.05 (95% CI = 1.77-2.37); Compared to a previous report, there were 4 additional  deaths from bladder cancer,  for a tot

SUBMITTER: Ciocan C 

PROVIDER: S-EPMC9073764 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature