Laser-Fabricated 2D Molybdenum Disulfide Electronic Sensor Arrays for Rapid, Low-Cost, Ultrasensitive Detection of Influenza A and SARS-Cov-2.

ABSTRACT: Multiplex electronic antigen sensors for detection of SARS-Cov-2 spike glycoproteins and hemagglutinin from influenza A are fabricated using scalable processes for straightforward transition to economical mass-production. The sensors utilize the sensitivity and surface chemistry of a 2D MoS₂ transducer for attachment of antibody fragments in a conformation favorable for antigen binding with no need for additional linker molecules. To make the devices, ultra-thin layers (3 nm) of amorphous MoS₂ are sputtered over pre-patterned metal electrical contacts on a glass chip at room temperature. The amorphous MoS₂ is then laser annealed to create an array of semiconducting 2H-MoS₂ transducer regions between metal contacts. The semiconducting crystalline

SUBMITTER: Muratore C 

PROVIDER: S-EPMC9073982 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature