The role of systemic immuno-inflammatory factors in resectable pancreatic adenocarcinoma: a cohort retrospective study.

ABSTRACT:

Background

Pancreatic cancer is an aggressive malignancy, surgery being the only potentially curative treatment. The systemic inflammatory response is an important factor in the development of cancer. There is still controversy regarding its role in pancreatic cancer.

Methods

Our study is a retrospective observational cohort study. We included patients diagnosed with pancreatic ductal adenocarcinoma (PDAC), who underwent surgical resection in our hospital, between January 2012 and December 2019. We gathered information from preoperative and postoperative blood tests. Neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), lymphocyte to monocyte ratio (LMR), prognostic nutritional index (PNI) and systemic immune-inflammation index (SII) were determined.

R

SUBMITTER: Schlanger D 

PROVIDER: S-EPMC9074307 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature