Verbal fluency response times predict incident cognitive impairment.

ABSTRACT:

Introduction

In recent decades, researchers have defined novel methods for scoring verbal fluency tasks. In this work, we evaluate novel scores based on speed of word responses.

Methods

We transcribed verbal fluency recordings from 641 cases of incident cognitive impairment (ICI) and matched controls, all participants in a large national epidemiological study. Timing measurements of utterances were used to calculate a speed score for each recording. Traditional raw and speed scores were entered into Cox proportional hazards (CPH) regression models predicting time to ICI.

Results

Concordance of the CPH model with speed scores was 0.599, an improvement of 3.4% over a model with only raw scores and demographics. Scores with significant effects included animals raw and sp

SUBMITTER: Ayers MR 

PROVIDER: S-EPMC9074715 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature