Body Composition and Incident Heart Failure in Older Adults: Results From 2 Prospective Cohorts.

ABSTRACT: Background Aging is associated with central fat redistribution and skeletal muscle decline, yet the relationships of tissue compartments with heart failure (HF) remain incompletely characterized. We assessed the contribution of body composition to incident HF in elders. Methods and Results Participants from 2 older cohorts who completed dual-energy X-ray absorptiometry (DEXA) and, in one cohort, computed tomography were included. We evaluated associations with incident HF for DEXA principal components (PCs) and total lean, appendicular lean, total fat and trunk fat mass; and for computed tomography measures of abdominal visceral and subcutaneous fat, thigh muscle, intermuscular fat area and thigh muscle density. DEXA analysis included 3621, and computed tomography analysis 2332 participant

SUBMITTER: Zhang L 

PROVIDER: S-EPMC9075203 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature