Post-Intracranial Hemorrhage Antithrombotic Therapy in Patients With Atrial Fibrillation.

ABSTRACT: Background To investigate the effectiveness and safety of withholding or restarting antithrombotic agents, and different antithrombotic therapies among patients with atrial fibrillation post-intracranial hemorrhage. Methods and Results This is a nationwide retrospective cohort study involving patients with atrial fibrillation receiving antithrombotic therapies who subsequently developed intracranial hemorrhage between January 1, 2011 and December 31, 2017. The risk of ischemic stroke (IS), recurrent intracerebral hemorrhage (ICH), and all-cause mortality were investigated between patients receiving no treatment versus patients reinitiating oral anticoagulants (OACs) or antiplatelet agents, and warfarin versus non-vitamin K antagonist OACs. We applied inverse probability of treatment weight

SUBMITTER: Lin SY 

PROVIDER: S-EPMC9075312 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature