Ontology highlight
ABSTRACT:
SUBMITTER: Humayun M
PROVIDER: S-EPMC9075809 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
Humayun Mouhita M Ayuso Jose M JM Park Keon Young KY Martorelli Di Genova Bruno B Skala Melissa C MC Kerr Sheena C SC Knoll Laura J LJ Beebe David J DJ
Science advances 20220506 18
Protozoan parasites that infect humans are widespread and lead to varied clinical manifestations, including life-threatening illnesses in immunocompromised individuals. Animal models have provided insight into innate immunity against parasitic infections; however, species-specific differences and complexity of innate immune responses make translation to humans challenging. Thus, there is a need for in vitro systems that can elucidate mechanisms of immune control and parasite dissemination. We ha ...[more]