A supramolecular hydrophobic guest transport system based on a biological macrocycle.

ABSTRACT: A protein-based macrocyclic bioactive guest loading system has been developed, which not only provides a stable 10 nm scale lipophilic environment, but also increases the solubility of potent anticancer agent SN38 in its active lactone form in aqueous medium.

SUBMITTER: Ge Y 

PROVIDER: S-EPMC9075912 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature