The balancing role of distribution speed against varying efficacy levels of COVID-19 vaccines under variants.

ABSTRACT: During a pandemic, vaccination plays an important role in reducing the infection spread or adverse outcomes such as hospitalizations and deaths. However, a vaccine's overall public health impact depends not only on its initial efficacy, but also its efficacy against emerging variants and ease and speed of distribution. For example, mutations in SARS-CoV-2 raised concerns about diminishing vaccine effectiveness against COVID-19 caused by particular variants. Furthermore, due to supply-chain challenges, the accessibility and distribution of the vaccines have been hindered in many regions, especially in low-income countries, while the second or third wave of the COVID-19 pandemic has occurred due to the variants. Hence, we evaluated the interactions between the speed of distribution and effic

SUBMITTER: Kim D 

PROVIDER: S-EPMC9075929 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature