Distinct representations of body and head motion are dynamically encoded by Purkinje cell populations in the macaque cerebellum.

ABSTRACT: The ability to accurately control our posture and perceive our spatial orientation during self-motion requires knowledge of the motion of both the head and body. However, while the vestibular sensors and nuclei directly encode head motion, no sensors directly encode body motion. Instead, the integration of vestibular and neck proprioceptive inputs is necessary to transform vestibular information into the body-centric reference frame required for postural control. The anterior vermis of the cerebellum is thought to play a key role in this transformation, yet how its Purkinje cells transform multiple streams of sensory information into an estimate of body motion remains unknown. Here, we recorded the activity of individual anterior vermis Purkinje cells in alert monkeys during passively appl

SUBMITTER: Zobeiri OA 

PROVIDER: S-EPMC9075952 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature