High pressure extraction of bioactive diterpenes from the macroalgae Bifurcaria bifurcata: an efficient and environmentally friendly approach.

ABSTRACT: The brown macroalgae Bifurcaria bifurcata have gained special attention due to their ability to biosynthesize linear diterpenes (rarely found in other species). However, the conventional extraction methods normally used to extract these compounds involve organic solvents and often high temperatures, leading to the degradation of thermo-labile compounds. In this context, the main objective of this work was to study and optimize for the first time the extraction of diterpenes from B. bifurcata through an environmentally friendly methodology, namely, high pressure extraction (HPE) using ethanol : water. This was compared with conventional Soxhlet extraction, using dichloromethane. Box-Behnken design was employed to evaluate the linear, quadratic, and interaction effects of 3 ind

SUBMITTER: Pais ACS 

PROVIDER: S-EPMC9076218 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature