Lung response to prone positioning in mechanically-ventilated patients with COVID-19.

ABSTRACT:

Background

Prone positioning improves survival in moderate-to-severe acute respiratory distress syndrome (ARDS) unrelated to the novel coronavirus disease (COVID-19). This benefit is probably mediated by a decrease in alveolar collapse and hyperinflation and a more homogeneous distribution of lung aeration, with fewer harms from mechanical ventilation. In this preliminary physiological study we aimed to verify whether prone positioning causes analogue changes in lung aeration in COVID-19. A positive result would support prone positioning even in this other population.

Methods

Fifteen mechanically-ventilated patients with COVID-19 underwent a lung computed tomography in the supine and prone position with a constant positive end-expiratory pressure (PEEP) within three days of

SUBMITTER: Protti A 

PROVIDER: S-EPMC9076814 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature