Ontology highlight
ABSTRACT:
SUBMITTER: Han F
PROVIDER: S-EPMC9077299 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
Han Fushi F Huang Dongdong D Meng Jinqian J Chu Jiapeng J Wang Meng M Chen Shuzhen S
Journal of cellular and molecular medicine 20220324 9
Radiotherapy is a common method for the treatment of lung adenocarcinoma, but it often fails due to the relative non-susceptibility of lung adenocarcinoma cells to radiation. We aimed to discuss the related mechanisms by which miR-126-5p might mediate radiosensitivity of lung adenocarcinoma cells. The binding affinity between miR-126-5p and EZH2 and between KLF2 and BIRC5 was identified using multiple assays. A549 and H1650 cells treated with X-ray were transfected with miR-126-5p mimic/inhibito ...[more]