Ontology highlight
ABSTRACT:
SUBMITTER: Chen J
PROVIDER: S-EPMC9077304 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
Chen Jungang J Barrett Lindsey L Lin Zhen Z Kendrick Samantha S Mu Shengyu S Dai Lu L Qin Zhiqiang Z
Journal of cellular and molecular medicine 20220322 9
Although small-cell lung cancer (SCLC) accounts for a small fraction of lung cancer cases (~15%), the prognosis of patients with SCLC is poor with an average overall survival period of a few months without treatment. Current treatments include standard chemotherapy, which has minimal efficacy and a newly developed immunotherapy that thus far, benefits a limited number of patients. In the current study, we screened a natural product library and identified 5 natural compounds, in particular tuberc ...[more]