Modular-Level Functional Connectome Alterations in Individuals With Hallucinations Across the Psychosis Continuum.

ABSTRACT: Functional connectome alterations, including modular network organization, have been related to the experience of hallucinations. It remains to be determined whether individuals with hallucinations across the psychosis continuum exhibit similar alterations in modular brain network organization. This study assessed functional connectivity matrices of 465 individuals with and without hallucinations, including patients with schizophrenia and bipolar disorder, nonclinical individuals with hallucinations, and healthy controls. Modular brain network organization was examined at different scales of network resolution, including (1) global modularity measured as Qmax and Normalised Mutual Information (NMI) scores, and (2) within- and between-module connectivity. Global modular organization was not

SUBMITTER: Schutte MJL 

PROVIDER: S-EPMC9077417 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature