Combined chemoradiotherapy showed improved outcome with early-stage HPV-positive oropharyngeal cancers.

ABSTRACT:

Background

The revised 8th Edition American Joint Committee on Cancer (AJCC) Head and Neck Staging Manual distinguishes HPV-mediated from non-HPV-mediated oropharyngeal cancer (OpSCC). The objective was to analyze OpSCC treatment modalities and outcomes.

Methods

A retrospective study of OpSCC patients treated with radiotherapy or chemoradiotherapy between January 1st, 2000, and December 31st, 2008, as identified from the BC Cancer Registry. All patients received treatment at cancer clinics and had at least 5 years follow-up post-treatment. A total of 1259 OpSCC patients were identified. After initial chart reviews, 288 patients were excluded from further analysis and the majority (n = 198) was due to not receiving curative treatment. Based on the availability of formalin-fix

SUBMITTER: Lu XJD 

PROVIDER: S-EPMC9077931 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature