A designable aminophenylboronic acid functionalized magnetic Fe₃O₄/ZIF-8/APBA for specific recognition of glycoproteins and glycopeptides.

ABSTRACT: We fabricated a novel aminophenylboronic acid functionalized magnetic Fe₃O₄/zeolitic imidazolate framework-8/APBA (denoted as Fe₃O₄/ZIF-8/APBA). First, Fe₃O₄ was coated by zeolitic imidazolate framework-8 (denoted as Fe₃O₄/ZIF-8) using the hydrothermal method. Next, the phenylboronic acid functionalized triethoxysilane reagent was synthesized by 3-aminophenylboronic acid and 3-isocyanatopropyltriethoxysilane, which was modified on the surface of the Fe₃O₄/ZIF-8 nanocomposite through the sol-gel technique and electrostatic interaction as well as π-π stacking interaction. The synthetic Fe₃O₄/ZIF-8/APBA exhibited high adsorption capacity and good specificity towa

SUBMITTER: Li S 

PROVIDER: S-EPMC9078308 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature