Anisotropic swelling wound dressings with vertically aligned water absorptive particles.

ABSTRACT: A multi-layer solution casting method was utilized to fabricate a three-layer wound dressing film consisting of a wound contact layer, an absorbing layer and a backing layer. The absorbing layer, whose function is to absorb and retain the exudate thus providing a moist environment for wound healing, was made of superabsorbent particles and a thermoplastic polyurethane matrix. In this study, the superabsorbent particles were aligned into chains whose axes oriented along the thickness direction of the film by an external electric field. This structure could minimize the lateral swelling of the absorbing layer while preferentially expanding in the thickness direction during the water absorption process, and therefore eliminate the lateral stress or shear induced friction between the films and

SUBMITTER: Guo Y 

PROVIDER: S-EPMC9078563 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature