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A novel fluorescent probe for imaging the process of HOCl oxidation and Cys/Hcy reduction in living cells.

ABSTRACT: A new on-off-on fluorescent probe, CMOS, based on coumarin was developed to detect the process of hypochlorous acid (HOCl) oxidative stress and cysteine/homocysteine (Cys/Hcy) reduction. The probe exhibited a fast response, good sensitivity and selectivity. Moreover, it was applied for monitoring the redox process in living cells.

SUBMITTER: Liu Z

PROVIDER: S-EPMC9078674 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature

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A novel fluorescent probe for imaging the process of HOCl oxidation and Cys/Hcy reduction in living cells.

Liu Zhen Z Li Guoping G Wang Yana Y Li Jiulong J Mi Yang Y Guo Linna L Xu Wenjian W Zou Dapeng D Li Tiesheng T Wu Yangjie Y

RSC advances 20180201 17

A new on-off-on fluorescent probe, CMOS, based on coumarin was developed to detect the process of hypochlorous acid (HOCl) oxidative stress and cysteine/homocysteine (Cys/Hcy) reduction. The probe exhibited a fast response, good sensitivity and selectivity. Moreover, it was applied for monitoring the redox process in living cells. ...[more]

PMID: 35541868

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