Metabotyping the Welsh population of badgers based on thoracic fluid.

ABSTRACT:

Introduction

The European badger (Meles meles) is a known wildlife reservoir for bovine tuberculosis (bTB) and a better understanding of the epidemiology of bTB in this wildlife species is required for disease control in both wild and farmed animals. Flow infusion electrospray-high-resolution mass spectrometry (FIE-HRMS) may potentially identify novel metabolite biomarkers based on which new, rapid, and sensitive point of care tests for bTB infection could be developed.

Objectives

In this foundational study, we engaged on assessing the baseline metabolomic variation in the non-bTB infected badger population ("metabotyping") across Wales.

Methods

FIE-HRMS was applied on thoracic fluid samples obtained by post-mortem of bTB negative badgers (n = 285) which were part of

SUBMITTER: Scott-Baumann J 

PROVIDER: S-EPMC9079023 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature