Multimorbidity Burden and Incident Heart Failure Among People With and Without HIV: The HIV-HEART Study.

ABSTRACT:

Objective

To examine the association between multimorbidity burden and incident heart failure (HF) among people with HIV (PWH) and people without HIV (PWoH).

Patients and methods

The HIV-HEART study is a retrospective cohort study that included adult PWH and PWoH aged 21 years or older at Kaiser Permanente between 2000 and 2016. Multimorbidity burden was defined by the baseline prevalence of 22 chronic conditions and was categorized as 0-1, 2-3, and 4 or more comorbidities on the basis of distribution of the overall population. People with HIV and PWoH were followed for a first HF event, all-cause death, or up to the end of follow-up on December 31, 2016. Using Cox proportional hazard regression, hazard ratios and 95% CIs were calculated to examine the association between mu

SUBMITTER: Mefford MT 

PROVIDER: S-EPMC9079699 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature