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A simple two-photon turn-on fluorescent probe for the selective detection of cysteine based on a dual PeT/ICT mechanism.

ABSTRACT: Herein, a simple two-photon turn-on fluorescent probe, N-(6-acyl-2-naphthayl)-maleimide (1), based on a dual PeT/ICT quenching mechanism is reported for the highly sensitive and selective detection of cysteine (Cys) over other biothiols. The probe was applied in the two-photon imaging of Cys in cultured HeLa cells, excited by a near-infrared laser at 690 nm.

SUBMITTER: Chen X 

PROVIDER: S-EPMC9079754 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature

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A simple two-photon turn-on fluorescent probe for the selective detection of cysteine based on a dual PeT/ICT mechanism.

Chen Xiani X   Xu Hang H   Ma Shengnan S   Tong Hongjuan H   Lou Kaiyan K   Wang Wei W  

RSC advances 20180410 24

Herein, a simple two-photon turn-on fluorescent probe, <i>N</i>-(6-acyl-2-naphthayl)-maleimide (1), based on a dual PeT/ICT quenching mechanism is reported for the highly sensitive and selective detection of cysteine (Cys) over other biothiols. The probe was applied in the two-photon imaging of Cys in cultured HeLa cells, excited by a near-infrared laser at 690 nm. ...[more]

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