Effect of surfactant on Pseudomonas aeruginosa colonization of polymer microparticles and flat films.

ABSTRACT: Micro- and nanoparticles are of great interest because of their potential for trafficking into the body for applications such as low-fouling coatings on medical devices, drug delivery in pharmaceutics and cell carriers in regenerative medicine strategies. Particle production often relies on the use of surfactants to promote stable droplet formation. However, the presence of residual surfactant has been shown to complicate the surface chemistry and resultant properties. When forming particles from polymerizable monomer droplets, these polymeric surfactant chains can become physically entangled in the particle surface. Due to the key role of the outermost layers of the surface in biomaterial interactions, the surface chemistry and its influence on cells needs to be characterized. This is the

SUBMITTER: Husler A 

PROVIDER: S-EPMC9079973 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature