Survival impact of previous statin therapy in patients hospitalized with COVID-19.

ABSTRACT:

Introduction

Statin therapy might have a beneficial prognostic effect in patients with COVID-19, given its immunomodulative, anti-inflammatory and anti-atherosclerotic properties. Our purpose was to test this hypothesis by using the COVID-19 registry of a Spanish university hospital.

Methods

We conducted a single-center, observational and retrospective study in which hospitalized patients with COVID-19 diagnosed by PCR between March 2020 and October 2020 were included. By means of logistic regression, we designed a propensity score to estimate the likelihood that a patient would receive statin treatment prior to admission. We compared the survival of COVID-19 patients with and without statin treatment by means of Cox regression with inverse probability of treatment weighting

SUBMITTER: Barge-Caballero E 

PROVIDER: S-EPMC9080058 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature