The application of existing genotoxicity methodologies for grouping of nanomaterials: towards an integrated approach to testing and assessment.

ABSTRACT: The incorporation of nanomaterials (NMs) in consumer products has proven to be highly valuable in many sectors. Unfortunately, however, the same nano specific physicochemical properties, which make these material attractive, might also contribute to hazards for people exposed to these materials. The physicochemical properties of NMs will impact their interaction with biological surroundings and influence their fate and their potential adverse effects such as genotoxicity. Due to the large and expanding number of NMs produced, their availability in different nanoforms (NFs) and their utilization in various formats, it is impossible for risk assessment to be conducted on an individual NF basis. Alternative methods, such as grouping are needed for streamlining hazard assessment. The GRACIOUS

SUBMITTER: Verdon R 

PROVIDER: S-EPMC9080165 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature