Long-term antibacterial performances of biodegradable polylactic acid materials with direct absorption of antibiotic agents.

ABSTRACT: In this study, polylactic acid (PLA) disks with antibacterial performances were prepared using 3D printing technology combined with direct adsorption of the antibiotic agents in solution baths. The effects of the layer thicknesses for the building of the 3D printing PLA disks and the amounts of antibiotic agents absorbed onto the sample surfaces on their antibacterial activities were investigated. The antibiotic agent release profiles from the samples surface into the buffer solution show that the antibacterial performances of these samples can reach up to 28 days. With a decrease in the concentration of antibiotic agent in the solution bath, the amount of antibiotic agent adsorbed on the sample surfaces also decreases, but their antibacterial performances can still maintain at least 7 day

SUBMITTER: Chen CH 

PROVIDER: S-EPMC9080263 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature