Assessment of EtQxBox complexation in solution by steady-state and time-resolved fluorescence spectroscopy.

ABSTRACT: Reliable chemical sensors with high selectivity and sensitivity toward specific target molecules require rational synthesis of receptors, in-depth characterization of their complexation abilities and highly efficient transduction of the molecular recognition event. Here we report a steady-state and time-resolved fluorescence investigation of EtQxBox, a fluorescent conformationally blocked quinoxaline-based cavitand, aimed at assessing its selectivity toward aromatic versus non-aromatic analytes in solution. Fluorescence quenching of the EtQxBox in acetone is observed at increasing concentration of both aromatic (i.e. benzonitrile) and aliphatic (i.e. acetonitrile) compounds. The combination with fluorescence lifetime measurements permits to discriminate the predominant

SUBMITTER: Aprile A 

PROVIDER: S-EPMC9080272 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature