Charge injection based electrical stimulation on polypyrrole planar electrodes to regulate cellular osteogenic differentiation.

ABSTRACT: In this study, polypyrrole (Ppy) electrodes were prepared to support an electrical stimulation to MC3T3-E1 cells for regulating their osteogenic differentiation. The charge injection capacity (C _Q) of the Ppy electrodes could be adjusted by the Ppy thickness, and a higher C _Q could make the electrode able to produce a higher charge injection quantity (Q _inj) at applied voltage. The Q _inj onto electrode could be considered as the intensity of the stimulation pulse to cells, and the pulse frequency means the number of electric stimulation with Q _inj at one second. Hence, we conducted the present work in the view of Q _inj. When the cells were electrically stimulated for 1 hour per day,

SUBMITTER: Liu Z 

PROVIDER: S-EPMC9080618 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature