Chemical studies on the parasitic plant Thonningia sanguinea Vahl.

ABSTRACT: Thonningia sanguinea Vahl plays an important role in traditional medicine in many African cultures. A study of the n-hexane fraction of the whole plant of T. sanguinea led to the isolation of two glucocerebroside molecular species TSC-1 and TSC-2, one β-sitosteryl-3β-d-glucopyranoside-6'-O-fatty acid ester molecular species, TSS-1, and seven known triterpenes (1-7). The ethyl acetate fraction also afforded five known lignans (8-12) and one known flavanone (13). Their structures were elucidated by means of chemical and spectroscopic methods (methanolysis, NMR and mass spectrometry). Spectral analyses of the glucocerebrosides revealed mainly sphingosine-type (TSC-1) and phytosphingosine-type (TSC-2) cerebrosides, with both possessing mainly 2-hydroxy fatty acid an

SUBMITTER: Thomford AK 

PROVIDER: S-EPMC9080861 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature