Sex-specific biomechanics and morphology of the anterior cruciate ligament during skeletal growth in a porcine model.

ABSTRACT: Pediatric anterior cruciate ligament (ACL) injuries are on the rise, and females experience higher ACL injury risk than males during adolescence. Studies in skeletally immature patients indicate differences in ACL size and joint laxity between males and females after the onset of adolescence. However, functional data regarding the ACL and its anteromedial and posterolateral bundles in the pediatric population remain rare. Therefore, this study uses a porcine model to investigate the sex-specific morphology and biomechanics of the ACL and its bundles throughout skeletal growth. Hind limbs from male and female Yorkshire pigs aged early youth to late adolescence were imaged using magnetic resonance imaging to measure the size and orientation of the ACL and its bundles, then biomechanically te

SUBMITTER: Howe D 

PROVIDER: S-EPMC9081289 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature