Esophageal Dysmotility Is Associated With Disease Severity in Eosinophilic Esophagitis.

ABSTRACT:

Background & aims

An association of eosinophilic esophagitis (EoE) with esophageal dysmotility has been described, however, the related mechanism remains unclear. We aimed to evaluate clinical and physiologic characteristics, including esophageal distensibility, associated with secondary peristalsis in patients with EoE.

Methods

A total of 199 consecutive adult patients with EoE (age, 18-78 y; 32% female) who completed a 16-cm functional luminal imaging probe (FLIP) during endoscopy were evaluated in a cross-sectional study. FLIP panometry contractile response (CR) patterns were classified as normal CR or borderline CR if antegrade contractions were present, and abnormal CRs included impaired/disordered CR, absent CR, or spastic-reactive CR. The distensibility plateau of the

SUBMITTER: Carlson DA 

PROVIDER: S-EPMC9081296 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature