Risk of Stroke Among Different Metabolic Obesity Phenotypes: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background and purpose

Overweight/obesity is a modified risk factor for stroke. This systematic review and meta-analysis aimed to assess the impact of different obesity phenotypes on stroke risk in adults.

Methods

The PubMed, Embase, and Cochrane Library databases were searched from their inception to 7 March 2021 to identify the prospective cohort studies investigating stroke risk among different metabolic overweight/obesity phenotypes. The methodological quality of the included studies was evaluated using the Newcastle-Ottawa Scale. Pooled hazard ratios (HRs) with 95% confidence intervals (CIs) were calculated using a random-effects model.

Results

A total of eleven prospective cohorts (n = 5,609,945 participants) were included in the systematic review, nine o

SUBMITTER: Meng M 

PROVIDER: S-EPMC9081493 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature