Iodine-promoted stereoselective amidosulfenylation of electron-deficient alkynes.

ABSTRACT: Iodine-promoted three-component synthesis of substituted β-amino sulfides has been developed starting from a propargyl ester, aliphatic secondary amine, and disulfide. This protocol provides a step-economic and highly regioselective entry to trisubstituted olefins with good substrate scope and functional group tolerance.

SUBMITTER: Xiao F 

PROVIDER: S-EPMC9081554 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature