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The synthesis of imidazo[1,5-a]quinolines via a decarboxylative cyclization under metal-free conditions.

ABSTRACT: An iodine-mediated decarboxylative cyclization was developed from α-amino acids and 2-methyl quinolines under metal-free conditions, affording a variety of imidazo[1,5-a]quinolines with moderate to good yields.

SUBMITTER: Yan Z

PROVIDER: S-EPMC9081590 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature

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The synthesis of imidazo[1,5-a]quinolines via a decarboxylative cyclization under metal-free conditions.

Yan Zicong Z Wan Changfeng C Yang Yu Y Zha Zhenggen Z Wang Zhiyong Z

RSC advances 20180625 41

An iodine-mediated decarboxylative cyclization was developed from α-amino acids and 2-methyl quinolines under metal-free conditions, affording a variety of imidazo[1,5-a]quinolines with moderate to good yields. ...[more]

PMID: 35540158

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