Baseline use of hydroxychloroquine or immunosuppressive drugs and the risk of coronavirus disease 2019.

ABSTRACT:

Background/aims

The preventive role of hydroxychloroquine (HCQ) on coronavirus disease 2019 (COVID-19) remains unclear. The aim of this study was to examine the effects of HCQ and other immunosuppressive drugs on the incidence of COVID-19.

Methods

The data were collected from the South Korea National Health Insurance Sharing-COVID-19 database. All individuals who underwent nasopharyngeal and oropharyngeal swab tests for COVID-19 from January 2020 to May 2020 are included. The association between COVID-19 risk and HCQ use was examined in a propensity score-matched population. Factors associated with COVID-19 were identified using multiple logistic regression analysis.

Results

Total 8,070 patients with COVID-19 and 121,050 negative controls were included from the databa

SUBMITTER: Kim JW 

PROVIDER: S-EPMC9082427 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature