Biological correlates of altered circadian rhythms, autonomic functions and sleep problems in autism spectrum disorder.

ABSTRACT: Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by a complex and multifaceted neurobehavioral syndrome. In the last decades, several studies highlighted an increased prevalence of sleep problems in ASD, which would be associated with autonomic system and circadian rhythm disruption. The present review aimed to summarize the available literature about sleep problems in ASD subjects and about the possible biological factors implicated in circadian rhythm and autonomic system deregulation in this population, as well as possible therapeutic approaches. Shared biological underpinnings between ASD symptoms and altered circadian rhythms/autonomic functions are also discussed. Studies on sleep showed how ASD subjects typically report more problems regarding insuffici

SUBMITTER: Dell'Osso L 

PROVIDER: S-EPMC9082467 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature