Determining the Clinical Course of Asthma in Pregnancy.

ABSTRACT:

Background

Asthma is the most common chronic disease affecting pregnancy, and poor asthma control has been associated with adverse pregnancy outcomes. However, the trajectory of asthma control during pregnancy is not well understood or characterized.

Objective

To identify and characterize trajectories of gestational asthma control in a US-based prospective pregnancy cohort.

Methods

A k-means algorithm for joint longitudinal data was used to cluster pregnant women with and without asthma into gestational asthma control trajectories on the basis of daily activity limitation, nighttime symptoms, inhaler use, and respiratory symptoms.

Results

Among 308 women with asthma, 2 trajectories of gestational asthma control were identified and labeled "same" (n = 184; 59.5%

SUBMITTER: Stevens DR 

PROVIDER: S-EPMC9082822 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature